Hmmmm interesting. Funny you mention it because I was taking gaba not too long ago and it was in a mixture with some other stuff. Anyways, I think it was causing me to wake up kind of uncoordinated and feeling just kind of weird. Dissociative I guess you could say, which makes sense because it’s related to the NMDA receptors somehow I think. It supposedly “can’t” cross the blood brain barrier, at least this is repeated despite the fact that it can and does, it’s just an unreliable mechanism in which it does. Low levels of gaba were insinuated to absorb more in the brain also. I didn’t have this issue as if I took the full 750 mg I felt very strange consistently and none of the other supplements in the mixture would seem to do this.
Alan: In the research I’ve collaborated on thus far, I unfortunately can’t report anything spectacular. In fact, it’s some of the most anticlimactic/unsexy results in the literature (LOL). However, in the most recent RCT of ours that’s in publication (PMID: 28070459), we did report individual data, and one of the subjects showed approximately an 18 mm gain in biceps thickness ( inches), measured via ultrasound, over an 10-week period. The rest of the subjects – all of whom were resistance-trained – stayed pretty much the same, which was not surprising since they were in hypocaloric conditions. It’s interesting to imagine what type of response this high responder would have if conditions were optimized for muscle growth, and/or supplementation was implemented. On the poor responder side, one of the subjects experienced a huge drop in quadriceps thickness (25 mm; about 1 inch) during this study. Interindividual response variability is just the nature of the beast, and a very poignant example of this is work by Ahtiainen et al (PMID: 26767377), who demonstrated vast heterogeneity in subjects’ responses to resistance training. Their study is openly accessible, have a look at this figure showing the full range of differences in strength & size gains (and losses): https:///pmc/articles/PMC5005877/figure/Fig4/. High responders gained 4-5 times the muscle mass of average responders. Of course there are the unfortunate subjects (2% of the subjects were classified as low responders) who included those who experienced losses in size and strength as a result of resistance training (and in my speculation, other factors as well).
I totally understand what kind of job you had. I work at a Wally World distribution center. Started in shipping, loading about 3 to 4 full semi’s a day. Didn’t know how much weight I loaded. Then switched to non conveyable. When in dog food, I’d stack about 60k/lbs in 12 hours. That was MUCH easier than shipping. My first year, I struggled. Then I talked to my bro-in-law, who is a personal trainer, found and I started to do good. I was taking creatine and C4 prior to work, and took an Animal Pak with UniLiver every break, while eating protien every 3-4 hours. This brought me to Muscle for Life and The Books. I’m in maintenance department now, and are about to join a gym. I’ve been wanting to get the Legion multi’s and switch to Legion supplements. I’m about done reading BLS, and are gonna start the year one challenge. I’ve aready bought BBLS and Shredded Chef. I get excited every time I think about my goals.