Side effects of steroid pulse therapy

Corticosteroids have been used as drug treatment for some time. Lewis Sarett of Merck & Co. was the first to synthesize cortisone, using a complicated 36-step process that started with deoxycholic acid, which was extracted from ox bile . [43] The low efficiency of converting deoxycholic acid into cortisone led to a cost of US $200 per gram. Russell Marker , at Syntex , discovered a much cheaper and more convenient starting material, diosgenin from wild Mexican yams . His conversion of diosgenin into progesterone by a four-step process now known as Marker degradation was an important step in mass production of all steroidal hormones, including cortisone and chemicals used in hormonal contraception . [44] In 1952, . Peterson and . Murray of Upjohn developed a process that used Rhizopus mold to oxidize progesterone into a compound that was readily converted to cortisone. [45] The ability to cheaply synthesize large quantities of cortisone from the diosgenin in yams resulted in a rapid drop in price to US $6 per gram, falling to $ per gram by 1980. Percy Julian's research also aided progress in the field. [46] The exact nature of cortisone's anti-inflammatory action remained a mystery for years after, however, until the leukocyte adhesion cascade and the role of phospholipase A2 in the production of prostaglandins and leukotrienes was fully understood in the early 1980s.

Testosterone is a male hormone that has anabolic and androgenic effects. The anabolic effect includes promoting bone density, the growth of muscle, and the rapid recovery from injury. The androgenic or masculinising effect is responsible for developing and maintaining all male characteristics. These include the penis, testicles, muscle mass, deep voice and facial hair.

Even though testosterone is called a male sex hormone, it occurs naturally in women as well, but in much smaller amounts. There are many legitimate medical uses for steroids, such as treating osteoporosis. However, men and women users who take steroids illegally do so to increase lean muscle mass. 

The abuse of steroids is most common among professional athletes and bodybuilders. Teenagers and adults who feel they need to look muscular to feel good about themselves may also abuse steroids.

There is no doubt that many of the physical side effects of steroid misuse and abuse can contribute to emotional and mental side effects and disorders.
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  Dangers of Injecting Steroids It’s not just physical and emotional/mental side effects that steroid users have to worry about.

Opinions vary greatly on the effects of steroid use. Although medical research is being conducted there is a divide amongst experts as to the effect of steroid use. Some of the users will write articles on the internet that is totally positive about the advantages of such use and the medical profession will write a negative article whilst both are discussing the same symptoms. It is well known that drug users will always try to justify their habit by producing facts and figures or even research that shows that their habit is not dangerous and causes no ill effects. The medical profession will offer views, supported by statistics that prove that drug use causes great harm, not only to themselves but to their families and friends indirectly. They will also argue that medical facilities are stretched by having to deal with self-inflicted illnesses and the weakness of those people taking steroids. Steroids are used by the medical profession to treat illnesses such as asthma and it is understandable that they resent misuse of such a drug when they are seeing the side effects that it has on their genuine patients. People will always be tempted by the lure of drugs as it is the lazy way to solve their problems and get a quick fix whether it is to enhance performance, to look better, or just to make them feel good temporarily.

Prednisone is a drug that belongs to the corticosteroid drug class, and is an anti-inflammatory and immune system suppressant. It's used to treat a variety of diseases and conditions, for example: inflammatory bowel disease (Crohn's disease and ulcerative colitis), lupus, asthma, cancers, and several types of arthritis.

Common side effects are weight gain, headache, fluid retention, and muscle weakness. Other effects and adverse events include glaucoma, cataracts, obesity, facial hair growth, moon face, and growth retardation in children. This medicine also causes psychiatric problems, for example: depression, insomnia, mood swings, personality changes, and psychotic behavior. Serious side effects include reactions to diabetes drugs, infections, and necrosis of the hips and joints.

Corticosteroids like prednisone, have many drug interactions; examples include: estrogens, phenytoin (Dilantin), diuretics, warfarin (Coumadin, Jantoven), and diabetes drugs. Prednisone is available as tablets of 1, , 10, 20, and 50 mg; extended release tablets of 1, 2, and 5mg; and oral solution of 5mg/5ml. It's use during the first trimester of pregnancy may cause cleft palate. This medicine is secreted in breast milk and can cause side effects in infants who are nursing. You should not stop taking prednisone abruptly because it can cause withdrawal symptoms and adrenal failure. Talk with your doctor, pharmacist, or other medical professional if you have questions about beta-blockers. Talk with your doctor, pharmacist, or other medical professional if you have questions about prednisone.

If you notice other effects not listed above, contact your doctor or pharmacist. In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Side effects of steroid pulse therapy

side effects of steroid pulse therapy

Opinions vary greatly on the effects of steroid use. Although medical research is being conducted there is a divide amongst experts as to the effect of steroid use. Some of the users will write articles on the internet that is totally positive about the advantages of such use and the medical profession will write a negative article whilst both are discussing the same symptoms. It is well known that drug users will always try to justify their habit by producing facts and figures or even research that shows that their habit is not dangerous and causes no ill effects. The medical profession will offer views, supported by statistics that prove that drug use causes great harm, not only to themselves but to their families and friends indirectly. They will also argue that medical facilities are stretched by having to deal with self-inflicted illnesses and the weakness of those people taking steroids. Steroids are used by the medical profession to treat illnesses such as asthma and it is understandable that they resent misuse of such a drug when they are seeing the side effects that it has on their genuine patients. People will always be tempted by the lure of drugs as it is the lazy way to solve their problems and get a quick fix whether it is to enhance performance, to look better, or just to make them feel good temporarily.

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