Steroid responsive dermatoses meaning

The most common side effect of topical corticosteroid use is skin atrophy. All topical steroids can induce atrophy, but higher potency steroids, occlusion, thinner skin, and older patient age increase the risk. The face, the backs of the hands, and intertriginous areas are particularly susceptible. Resolution often occurs after discontinuing use of these agents, but it may take months. Concurrent use of topical tretinoin (Retin-A) % may reduce the incidence of atrophy from chronic steroid applications. 30 Other side effects from topical steroids include permanent dermal atrophy, telangiectasia, and striae.

Because steroids are lipophilic, they diffuse easily through the cell membranes, and therefore have a very large distribution volume. In their target tissues, steroids are concentrated by an uptake mechanism which relies on their binding to intracellular proteins (or " receptors ", see below). High concentration of steroids are also found in adipose tissue, although this is not a target for hormone action. In the human male, adipose tissue contains aromatase activity, and seems to be the main source of androgen-derived estrogens found in the circulation. But most of the peripheral metabolism occurs in the liver and to some extent in the kidneys, which are the major sites of hormone inactivation and elimination, or catabolism (see below).

Follow-up appointments will be very important and absolutely necessary with a diagnosis of steroid-responsive meningitis-arteritis. Your veterinarian will determine the schedule of the return visits which will depend on how well your furry family member responds to the treatment. The follow-up will mean repeat blood tests and analysis of the CSF until the veterinarian can see that the markers have returned to normal. This could mean appointments every 4 to 6 weeks for several months. It is imperative that you keep the appointments and do not discontinue the medication even though you may think your dog is feeling better. It should be noted that many pets will need a prescription for gastroprotectants; if you see any side effects from the long-term therapy such as blood in the stool or vomiting, or if you are concerned in any way with your pet’s health, contact the clinic without delay. With SRMA there is a potential for relapse, meaning that continued contact with your veterinarian will be recommended.

Steroid Responsive Meningitis - Samantha Goldberg BVSc MRCVS

Neck Pain and Fever in a Boxer--NAVA Clinician's Brief, November 2009
The Five Minute Veterinary Consult Page 388,
J AM Vet Med Assoc 201[10]:1553-8 Nov 15'92--Systemic Necrotizing Vasculitis in Nine Young Beagles.
J Vet Inter Med 4[2]:112 Mar/Apr'90 ACVIM 8th Annual Forum--Systemic Vasculitis {Canine Pain Syndrome} in young beagles
J Vet Intern Med 2[1]:26-35 Jan/Mar'88 123 Refs--Canine Meningitis:A Changing Emphasis
The Veterinary Record, June 17, 1978--Polyarteritis in a colony of beagles.
The Veterinary Record, April 7th 1973--Polyarteritis in the Dog: A Case Report   Dr. Roughie’s Questions and Answers- Steroid Responsive Meningitis-Vasculitis: The Disease With Many Names   Kasmin D. Bittle DVM   /images/Health/Dr-Roughie-ST-Column/
Neck Pain By Dr. J. E. Dillberger,  /images/Health/Dr-Roughie-ST-Column/

Steroid responsive dermatoses meaning

steroid responsive dermatoses meaning

Steroid Responsive Meningitis - Samantha Goldberg BVSc MRCVS

Neck Pain and Fever in a Boxer--NAVA Clinician's Brief, November 2009
The Five Minute Veterinary Consult Page 388,
J AM Vet Med Assoc 201[10]:1553-8 Nov 15'92--Systemic Necrotizing Vasculitis in Nine Young Beagles.
J Vet Inter Med 4[2]:112 Mar/Apr'90 ACVIM 8th Annual Forum--Systemic Vasculitis {Canine Pain Syndrome} in young beagles
J Vet Intern Med 2[1]:26-35 Jan/Mar'88 123 Refs--Canine Meningitis:A Changing Emphasis
The Veterinary Record, June 17, 1978--Polyarteritis in a colony of beagles.
The Veterinary Record, April 7th 1973--Polyarteritis in the Dog: A Case Report   Dr. Roughie’s Questions and Answers- Steroid Responsive Meningitis-Vasculitis: The Disease With Many Names   Kasmin D. Bittle DVM   /images/Health/Dr-Roughie-ST-Column/
Neck Pain By Dr. J. E. Dillberger,  /images/Health/Dr-Roughie-ST-Column/

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